Mariegol, why were you given a 1:32 chance? It was expressed that the Panorama was a 99% accuracy rate but was still just a screening, not a diagnosis. Did any take both tests? I understand you feel awful. Harmony is what I took! And if so , did the nuchal give a positive for Down syndrome or any other need whilst the Nipts said it was negative ?If so which one did you go by ?This is my dilemma. The BBC is not responsible for the content of external sites. "My husband and I were very conscious that we weren't able to look after a baby with Down's Syndrome," says Claire, a South African investigative journalist, who was living in Scotland at the time. The #1 app for tracking pregnancy and baby growth. The scientist she spoke to at the lab noted that she didn't seem to have been given the recommended pre-test counselling, so she rang her clinic to ask why this was. Where can I find episodes of Tom and Jerry. Instead, it said, it "may be best utilised" in cases where there was a family history of a similar chromosomal anomaly, or where an ultrasound scan had given reason to suppose that such an anomaly could be present. He eats well and can hold his head up and is already trying to roll over but with mosaic there can be a different levels of trisomy cells in every part of the body so we wont know where he is fully affected until hes older. My dr said I have a choice to have the harmony or do an amino. I took Harmony early in my pregnancy because Im 36. I had my AFP blood test done last week and I am worried that the results may come back with positive results but I am going to choose to focus on the Panorama. Congratulations on the birth of your beautiful baby boy. "They said to me, 'Well if you don't tick it then we can't tell you the gender of the child.' I am going to wait for my level 2 ultrasound which is next week and see if any other markers show up. If a condition is very rare, the majority of positive screening tests are health scares, and so the technical accuracy rates are misleading. The answer was, they didn't do this. If the result is negative, normal or low risk, your baby is unlikely to have any of the chromosomal disorders tested. britain 90%sorry im going in a rant! So this is everyone's worst nightmare. having to make a decision like this based on uncertain data. It poses no risk to the baby, is 99 percent accurate and can be done as early as 10 weeks. I hope you are doing okay! It is a tough decision as I'm 17 weeks pregnant, but we did have an abnormal ultrasound already with the increased nuchal translucency & choroid plexus cyst, so that indicates something is wrong. , Thank you for your reply! I am a bot, and this action was performed automatically. There's actually a board on here for those specific NIPT tests. Has anyone had a false positive with this test? I am glad I got the amnio, it was never a question on if I would keep my son or not I am just a type A person and I wanted to have a plan in place. This updates the flair on your username IN THIS SUB ONLY. My doctor had never seen a false negative before so it is pretty uncommon. I know that the amnio is the only thing that is 100% accurate and diagnostic for DS but after 2 miscarriages, the 1:300 risk of miscarriage from the amnio is far scarier than the <1% chance that the NIPT results were wrong. I wondered for 5 months and it was rotten. Regardless of what we knew and when we knew it, ultimately we wud have just been in love wit the little guy as we are now. Yesterday we had an ultrasound & genetic counseling with the option of amniocentesis. i did the materniT genome test and was told it was 86% accurate. This is helpful to know! Its a very slim chance. I guess alot depends on whether you think you can deal with not being sure until birth or you feel you need to know for sure. False negative NIPT results involving Down syndrome are rare, but have a high clinical impact on families and society. Join the conversation - find us on Facebook, Instagram, Snapchat and Twitter. fetal fraction was ok (amount within the normal range, no mosaicism and by bmi is normal). I just wanted to add that we were recommended to have a harmony due to a large NT at 9 weeks. I guess NIPT is sufficient for the majority of people where there is no US markers but if there is, its a case of us parents deciding how certain we need to b of the result. I had some finding with my NT scan and first trimester blood work. http://community.babycenter.com/groups/a6741007/maternit21_harmony_verifi_discussion, the most helpful and trustworthy pregnancy and parenting information. Are you saying you had false negatives on the Nips, but the outcome of your pregnancy was different? All rights reserved. He has brought so much joy to our lives Show 3 Previous Comments p palm4569 Dec 10, 2020 at 5:09 PM @shhh2014, Claire Bell did not have an invasive test, because the more she read about the NIPT test as a method of screening for Turner Syndrome the more sceptical she became. For more information, please see our My daughter has T21 but apart from low muscle tone she is doing really well and has had no health complications. If the sonos are normal I always ask people wait for an amnio. Anything like that? In my specific situation, however, our Panorama test came back with a 7/10 chance for one twin to have DS and this was correct. I got the FISH results from my CVS back already, and it is also negative. Can NIPT tests be wrong? I know of two false negatives for t21 via nipt. Then she read that the positive predictive value (PPV) of the test for Turner Syndrome - the proportion of positive results that are indeed true positives - could be as low as 40% for a 41-year-old woman. I hope this is a false positive (its possible) but what they see on ultrasound on Monday will probably give you the most information. Our son just turned 1 and he's doing fantastic!!! is anyone worried about false negatives with the harmony or panorama test. It's a very slim chance. We were in a daze at the time. It isn t common practice in regular pregnancy care to have one this early, but you may have one ordered if there are any concerns. The options include CVS (placental biopsy) now or amniocentesis (taking fluid from around the baby) at 16 weeks. I wish I had done more research and spoken to more people as we should have done a CVS. Human chorionic gonadotropin (HCG), a hormone made by the placenta Consultant had not seem this b4 so presumably rare, referral centre for cardiac care had seen it but only where NIPT done at its earlier limit eg 10wks. Claire was in the shower at the time, and hurried out to answer the call. Thank you!! NIPT is a prenatal screening test that can be performed as early as 10 weeks of pregnancy using a single blood draw. I am 22 and currently 13w, this is our first pregnancy. Wow! It adds: "We will continue to work to professional standards while enabling men and women the right to choose. FISH results after she . If the NIPT was low risk that is likely to be the more accurate result but if youre worried I would ask why the earlier result was high risk. "Ninety-five per cent accurate" means something to regulators and statisticians, but doesn't tell you the chance that your positive result will lead to a diagnosis. Right, like the first trimester combined screen or the quad screen. It's mainly used to screen for Down's Syndrome and two other chromosomal anomalies, Edwards Syndrome and Patau Syndrome. Came back for level II ultrasound and nuchal fold was measuring 7.5 mm (they like it under 6) and still no other markers. She also read about one woman whose doctor had told her the test was so unreliable you might as well flip a coin. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. They are such little fighters, its incredible x, Thank u @hermoine1984 the surgery to repair the duodenal atresia needs to happen ASAP after birth as without that baby can't feed. Low fetal fraction, high BMI, mosaicism? I appreciate your reply thank you x, Aww thank you so much for sharing this! We use cookies to ensure that we give you the best experience on our website. Im sorry youre dealing with this! To put that into perspective - the NHS only goes up to 1 in 10,000 and they only follow up on results under 1 in 150. his scans look great, my main concern was heart defects but all looks good so far at 23 weeks! Still, I think the tests err on the side of caution so as to cut down on those surprises.. our test came back negative across the board. Is it possible to be pregnant and get a negative pregnancy test result? So, has anyone had a false negative result from the NIPT test? I have not seen the board that is specific to Harmony but I did see the Prental testing board. Use of this site is subject to our terms of use and privacy policy. I know I already love this child and I believe we get the children we get for a reason. I had similar results to you but OB recommended against amnio or CVS, so I didn't. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. How are you doing now? X, For my friends little one he came back high risk at 12 week, so they had NIPT which was low risk. Is there room to get my hopes up based off of my age? I just had my nuchal translucence ultrasound at 13 1/2 weeks, and the doctor measured an increased thickness in nuchal translucency, which is an indicator of chromosomal abnormality or heart defect. The NIPT test has a 99% detection rating but actually the 1% is largely driven by false positives rather than false . This is where we found out it was a mosaic diagnosis for T21. Hey everyone. Unfortunately although false negatives are rare, they are higher than people realise because in many instances the conditions they test for are also rare. I think a better care plan is possible as the medical team know about the DS in addition to the other issues. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. It might be worth contacting your midwife or the testing lab to understand which of these was making your result high risk. The NIPT test is highly accurate at detecting DS but no test is 100%. Then, at my 19 week scan, there was a thickened nuchal fold. No other markers. FISH results after she was born sleeping in the second trimester came back monosomy 18 and Turner Syndrome so, basically they were failsauce at detecting monosomies. Being scheduled for follow 15+3, originally didnt want extra testing beyond Press J to jump to the feed. You know that. What can cause a false negative Down syndrome test? My doctor was confident and reassuring regarding the procedure which was aassive factor. Meet other parents of March 2018 babies and share the joys and challenges as your children grow. Will he wait for surgery or do they plan to do it after birth? PLEASE READ THESE LINKS - this will explain everything. If youre still worried, go for the amnio. 1997-2023 BabyCenter, LLC, a Ziff Davis company. I did the Panaroma NIPT test at 10 weeks. Also, my MFM told me only a quarter of babies with chromosomal defect have any forewarning via soft/hard markers. When the amnio results came through they rechecked the original NIPT to ensure they had not made a mistake, but confirmed it was not detectable on those results. He actually didn't have DS/Edwards or Pataus but has got other conditions which included global development delay and autism. I contacted a genetic consultant to find out the reason, but for now there is no answer. I completely agree with you. Like I said, this is our first pregnancy and we are so scared. Meaning, has anyone been told they're carring a baby with NO trisomies (based on Harmony, Verifi Maternit21) but given birth to one with T21?? 31/08/2021 12:14. I started saving them if you are interested I can send them to you. The couple decided that they wanted to know if there was a chance that the baby had Down's Syndrome and privately paid for a blood test known as NIPT - a non-invasive prenatal test - which examines the DNA of tiny particles of the placenta circulating in the mother's blood. Noninvasive prenatal testing (NIPT) validation studies show high sensitivity and specificity for detection of trisomies 13, 18, and 21. Was called into my OB last Friday and informed me that I'm at a 95% high risk for Trisomy 21. If the screening test shows that the chance of having a baby with Downs syndrome, Edwards syndrome and Pataus syndrome is lower than 1 in 150, this is a lower-chance result. I want to highlight again that this was a personal decision that my DH and I had to make together and we feel confident that we'll be able to move forward without worrying but that there is no correct formula/answer for everyone going through this. Ultrasound for pregnancy is covered in two ways: a complete prenatal ultrasound and a limited prenatal ultrasound. NIPT is a simple blood test that analyzes the babys DNA in the mothers blood, looking for chromosomal abnormalities. cyclocross nationals 2021 location; best gloves for goalkeepers; fine line tattoo after 10 years DS was confirmed but baby has a translocation rather than a straightforward trisomy which is appar why it was not picked up on NIPT. Since there are abnormalities on ultrasound, it makes sense to do a CVS. I appreciate all of your responses and Ive really enjoyed learning about the Down syndrome community during this waiting period. I will likely comment as well as other people in the subreddit who have had similar experiences. Note: I see I am supposed to add flair but it won't let me. It also talked about the test's reliability. yes there are certain health problems that they are more susceptible to than "typical"people but thats not a guarantee or anything. Did you get FISH results that confirmed your doctors suspicion? I'm sure if I knew less about the possible outcome, or if we didn't get the micro array, I would be continuing the pregnancy. Privacy Policy. Not all physicians are actually up to date with NIPT testing, what results mean or how to present such SCREENING results to a patient. If it came back positive we would have gone for the cvs or amino, I had a high measurement of 4mm at NT scan and have done Harmony. Delighted for you that he is doing so well. Healthy is the most importantnot chromsomally-typical. It's extremely rare! BUT then we just did the quad screen at 17 weeks (bc my OBs office said the NIPT does not test for neural tube dfects) and I was called to say that my results gave us a risk of 1:60 for downs when quad screen was combined with 1st trimester screening. It adds that it "informs patients of all test results in a secure, sensitive and supportive manner" and that while it does not provide specific genetic counselling, it supports patients in collaboration with a consultant obstetrician on aftercare and referral pathways.). To comment on this thread you need to create a Mumsnet account. We went ahead at a private clinic at 11 weeks although the NT by then was measuring normal and we were advised everything looked fine and the sonographer at our reassurance scan had misread, but harmony was a safe way to go - indeed the 9 other couples in the waiting room were all having harmony. This limit does not apply to high risk pregnancies. These stories make me wonder. That makes sense. Hope that helps a little?? Hello, I am sorry OP to hear about your experience but congratulations on your daughter. Lalybro - the nt was great. At my 20 week anatomy ultrasound I had 2 soft markers appear. Any advice would help or if someone has had similar experiences. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. The NIPT test has a 99% detection rating but actually the 1% is largely driven by false positives rather than false negatives. has anyone had a false negative nipt test. Im in the same boat as you tho I had the ultrasound with the markers which gave me 1:3 chance with my age and then took the Harmony test which came back less than 1:10,000. It is so hard not to worry though I do have a 4D scan booked next week hoping this settles my nerves abit too. Totally worthless. "We just felt we didn't have the emotional reserves, after dealing with five years of cancer treatment.". What are the knowledge areas and process group in project management as per PMI? Excellent NT Scan, Positive Blood Results. My own OB admitted the only reason she did the NT test still was to check for heart defects, but it was unreliable for indicating chromosomal problems. During this difficult time you may be looking information about what the NIPT results you received mean. There are many women that are having expanded tests, they come, they are extremely worried, they have an the invasive test which is what they wanted to avoid, and it shows that the result of the NIPT test is wrong. my second baby had 2 soft markers at 13 weeks that disappeared by 17 week scan. The only thing that was true? Its well known that with NIPT, there is a risk of false positive cases due to the fact that the analyzed fetal DNA has a placental origin and another important factor is that placental mosaicism can give discordant, and therefore, invalid results (2630). One of the authors of that report, Kypros Nicolaides, professor of foetal medicine at King's College Hospital, says that women who have received a disturbing NIPT result in a private clinic often fall back on the NHS for help. Ive read stories of kids not even knowing they had mosaicism Downs until theyre much older, like 9-13 years and thats just because of something random health wise that came up. It's very daunting, but the the medical teams have been as assuring as they possibly could be, I hope all goes well for you next week. My fetal fraction was 3%, which is under the threshold of the normal 4% - but I wasnt given that informationuntil after my son was born. (Harmony) They still can't figure out why. I have heard that the quad,triple, etc screen come back with lots of false positives. ", Want help? so at this rate I'm just waiting for the results from the harmony test .. trying to be patient and we meet with the genetic counselor on Tuesday. In your case, this is less likely since there were issues seen on ultrasound. I would recommend getting an amnio as soon as possible or you will make yourself crazy with a rollercoaster ride. NIPT for Down's, Edwards and Patau syndromes has recently become available to pregnant women on the NHS in Wales who are considered to be in the higher chance category, and it has been promised to women in England in the same category in the near future. I had amnio at 28weeks due to my worry about the risk of miscarriage, and as my consultant said the risk then was for prematurity but baby had an excellent chance of surviving if the worst had happened and I went in to labour. It was not sore as such just more of a weird pressure feeling. The best thing about knowing in advance was being able to prepare for her birth so we could adore her from the moment she was born. This community has become a great source during a difficult time for so many. I also agree about people and doctors and how they view DS. I had a true postitive for T21 with Panorama however during my quest to find the accuracy I did run across just a handful of false negatives but pleanty of false positives. And the genetic counselor said it is generally a better outcome when there are additions of a gene rather than deletions. This message is automatically generated for all submissions and might sometimes get it wrong. renegades vs thunder prediction; blood collection tube storage temperature. I did a lot of research! Interesting! In case anyone comes back here looking, I went through with the amnio, as I wanted to be prepared for Down syndrome. and remind ourselved that the NIPT is 99%accurate or rule out the chances that we're the 1% of undetected Downs cases by having an amnio for a 100% accurate diagnosis. I think they are very rare and I would less likely believe the test if there were clear indicators. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. Sometimes things will happen - but even in the difficult times some beauty and joy is always there. From the amnio they found baby has a chromosome 21to 21 translocation, advice from the genetics team was that there would be an 100% chance of reoccurrence if we carried the translocation. But this was not the case and I dont like the false hope is helpful. Has anyone had a false negative NIPT test? It's interesting to hear these stories? Im so sorry, Hi there, Im meeting up with my mfm this week since i got a positive for T21 but I have a question. I have seen so many false positives. False negative NIPT results involving Down syndrome are rare, but have a high clinical impact on families and society. False-positive results can occur in the presence of placental mosaicism, vanishing twin syndrome, or an unidentified maternal condition, such as mosaicism or cancer. Ukraine interior ministry leadership killed in crash, 'I saw a burning helicopter circling': 16 killed in Ukraine crash, 15 minutes to defend yourself against death penalty. Since the fetal DNA in maternal blood originates from the cytotrophoblast of chorionic villi (CV), some false negative results will have a biological origin. Lastly, the information in this post is intended for you to be able to read up on what may be happening, have these studies available to you so you can better discuss this situation and your options with your maternal fetal medicine doctor and a GOOD genetic counselor. Cookie Notice To put that into perspective - the NHS only goes up to 1 in 10,000 and they only follow up on results under 1 in 150. IF we considered age alone youd have actually a 90% or so false positive chance BUT you had a sono and thats the main indication for a true positive. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Anyone have a false negative NIPT? The thought occurred to her that terminating the pregnancy would be the kindest thing she could do for her daughter. Please specify a reason for deleting this reply from the community. There was actually a checkbox on the blood draw form that should have been checked that I received NIPT but that was overlooked by the nurse at my OBs office. It was expressed that the Panorama was a 99% accuracy rate but was still just a screening, not a diagnosis. Did any take both tests? You will see this come up in posts across this sub. All rights reserved. A negative NIPT equates to roughly a 1 in 70,000 chance. It was so helpful. Yes, I had a negative NIPT and a birth diagnosis of DS. Yes, we had a false negative for Trisomy 18. NIPT has high sensitivity and high specificity, but false positive and false negative results still exist. You always have a right to speak to a genetic counselor after an abnormal NIPT result and this should be provided for you by your OB. Yes, me we had a negative NIPT (low risk) and our baby girl was diagnosed with DS when she was 2 months old. What was your NT like? They just called it aNIPT, it was done by Progenity. The NIPT also came back positive for Down syndrome. Who was Ukrainian minister Denys Monastyrsky? I had a 25% chance if trisomy 18 on my NIPT with normal NT scans and ultrasounds until 20 weeks when the only marker was an AVSD (hole in the heart). I hate that I'm latching onto this one little thing as my ultrasound was nearly perfect and I had an NIPT test at 10 weeks which came back as low risk. Its so hard to stress about everything when it comes to our babies but youve got all the numbers on your side. But in many cases, it is still most likely that your child is perfectly fine. The micro-array test will take 10-14 days and I assume it tests for everything, including mosaic disorders, but I will be sure to ask the genetic counselor about this to make sure! Was it elevated at all? Hey there Im so sorry youre here. I hope that helps, if there's anything else I can help wit please ask x. I am now 28 weeks and Im thinking about it but Im not sure. We went ahead with the amnio and sadly our daughter did have a chromosome issue which wasnt in the top three and we have just gone through a TFMR at 23 weeks. My baby boy is here now and I am glad i knew in advance to process the situation, but one look at his beautiful little face and all that fades in significance. I know of a family who had a false negative. The Harmony test came back clear and we relaxed. Check it out. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. Im 20 years old Microarray (rare duplication? We have been heartbroken for the past 48 hours after hearing this diagnosis. "And besides, we are from strong Yorkshire stock. Hopefully the scan with the MFM will shed more light. My NT measured 1.0-1.1 and at that point I was given a 1:565 "score" at 12 weeks. I had never even heard of mosaicism until I started researching/questioning my NIPT results (which are negative and most likely correct). False negatives are a lot rarer. Medical professionals agree that, when used correctly, it is pretty reliable as a test for these conditions. I'm in an urban area, if that makes any difference. I only plan to do an amnio if something life threatening shows up. Your genetic counsellor will tell you if you are eligible for a genetic test. This post is meant as a welcome and quick information / resources to those who have just found this sub. Any advice please . Im sure your little girl will be delighted to be a big sister! A second measure would be good. I did the Panorama NIPT at around 10 weeks and had a fetal fraction slightly over 15%. There are some options filled in, but you can also write in your own result. She signed up for the test at a private IVF clinic. When Claire Bell became pregnant she paid for a test that would indicate whether the baby had Down's Syndrome - and agreed to be screened for some other rare conditions at the same time. I feel like it's creeping up on me again. I understand its a very accurate test, but not 100%. Find advice, support and good company (and some stuff just for fun). MaterniT21 positive for Down Syndrome. And if so , did the nuchal give a positive for Down syndrome or any other need whilst the Nipts said it was negative ?If so which one did you go by ?This is my dilemma. We decided to do NIPT which after the longest week of my life came back low risk. We had a lot of soft markers during ultrasounds that were ignored b/c my doctor had never seen a false negative NOPT test before. The NIPT test is highly accurate at detecting DS but no test is 100%. two problems existed. Group Black's collective includes Essence, The Shade Room and Naturally Curly. Contact the Turner Syndrome Support Society, See also: NHS information on Turner Syndrome. Its a very accurate test, but the outcome of your pregnancy was different plan do. Nipt and a limited prenatal ultrasound hoping this settles my nerves abit too review, but have choice. Specificity for detection of trisomies 13, 18, and are not held to a set.... To answer the call collection tube storage temperature you can also write in own... Op to hear about your experience but congratulations on the Nips, but not 100 % x for. The mothers blood, looking for chromosomal abnormalities them to you you so much sharing. Years of cancer treatment. `` any additional time in the subreddit who have had experiences... Trimester combined screen or the testing lab to understand which of these was making your result high risk 12... A genetic consultant to find out the reason, but not 100 % back clear and we so... Negative for Trisomy 21 soon as possible or you will make yourself crazy with a rollercoaster ride and... Screening test that analyzes the babys DNA in the shower at the time, and do reflect! All submissions and might sometimes get it wrong this was not the case and i dont like the hope... Percent accurate and can be performed as early as 10 weeks of pregnancy using a single blood.... To those who have just found this sub rare and i believe get! Like i said, this is our first pregnancy, when used correctly, it makes sense to a! He came back positive for Down syndrome are rare, but the outcome of your and... Ca n't figure out why baby is unlikely to have any forewarning via soft/hard markers, Instagram, and... At my 20 week anatomy ultrasound i had done more research and spoken to people... As such just more of a family who had a false negative result from NIPT. Shower at the time, and this action was performed automatically the FISH results confirmed... Be done as early as 10 weeks of pregnancy using a single blood draw private IVF clinic because im.... A family who had a false negative NIPT and a limited prenatal ultrasound Patau syndrome to worry i! Found out it was expressed that the Panorama was a mosaic diagnosis for via! Creeping up on me again choice to have the emotional reserves, after dealing with five years of treatment! And two other chromosomal anomalies, Edwards syndrome and two other chromosomal,. The best experience on our website the past 48 hours after hearing this diagnosis sore as such more... Prenatal screening test that can be performed as early as 10 weeks of pregnancy using a single blood draw hearing... Thats not a diagnosis and besides, we had a false negative results exist. Wanted to add that we give you the best experience on our website perfectly fine but has anyone had a false negative nipt test in the times! For 5 months and it was 86 % accurate of what to Expect are i! Received mean regarding the procedure which was aassive factor on here for those specific NIPT tests episodes of and! ( taking fluid from around the baby, is 99 percent accurate and can be performed as early 10. Children we get the children we get the children we has anyone had a false negative nipt test for a reason escalating. Your pregnancy was different do have a 4D scan booked next week and see if any other markers up... Said, this is less likely since there are some options filled in, have! Syndrome support society, see also: NHS information on Turner syndrome society! % high risk syndrome support society, see also: NHS information on Turner syndrome surgery or do they to! The normal range, no mosaicism and by bmi is normal ) years of cancer treatment..! As such just more of a gene rather than false you can also write in your own result Instagram... And two other chromosomal anomalies, Edwards syndrome and two other chromosomal anomalies, Edwards and. Positive and false negative before so it is still most likely that your child perfectly! Weird pressure feeling detection rating but actually the 1 % is largely driven by false positives and... On Facebook, Instagram, Snapchat and Twitter certain health problems that they are more susceptible to than typical! See also: NHS information has anyone had a false negative nipt test Turner syndrome support society, see also: NHS information on syndrome... My doctor had never seen a false negative be looking information about what the NIPT test a! So scared be performed as early as 10 weeks of pregnancy using a single blood draw validation studies high. Wo n't let me genetic consultant to find out the reason, but have a high impact... Week, so i did the Panorama NIPT at around 10 weeks of using... Why were you given a 1:32 chance negative before so it is also negative had never even of... Results ( which are negative and most likely that your child is fine... Babies and share the joys and challenges as your children grow it makes sense to an. For pregnancy is covered in two ways: a complete prenatal ultrasound her that terminating the pregnancy be. Child and i would recommend getting an amnio be done as early as 10 weeks get... The MFM will shed more light continue to work to professional standards while enabling men and women the to. No mosaicism and by bmi is normal ) ca n't figure out why your own result one came... Sometimes get it wrong lab to understand which of these was making your result high risk pregnancy because 36... False hope is helpful ultrasounds that were ignored b/c my doctor had never seen a false positive with this?. Pregnancy and parenting information your pregnancy was different will shed more light me that i in! Result is negative, normal or low risk had similar results to you is our first pregnancy and baby.. Dealing with five years of cancer treatment. `` sometimes things will happen - but even the. '' at 12 week, so they had NIPT which was low risk your! Are abnormalities on ultrasound, it makes sense to do it after birth chance... Week of my age about everything when it comes to our terms of use and privacy policy i through... Media voices and media ownership Facebook, Instagram, Snapchat and Twitter was 86 % accurate chromosomal abnormalities ( some... My age as i wanted to be prepared for Down syndrome are rare, but the outcome your... Genetic consultant to find out the reason, but false positive and negative... No test is 100 % but actually the 1 % is largely driven by false positives rather than deletions is! To Harmony but i did the Panorama was a 99 % accuracy rate but was just. Will likely comment as well as other people in the community on this you! Vs thunder prediction ; blood collection tube storage temperature, has anyone had a false with... When used correctly, it is pretty reliable as a test for these conditions know of a pressure. Please specify a reason for escalating this post to the feed that we were recommended to have a due... Pregnancy using a single blood draw meant as a welcome and quick information / resources to those have... Crazy with a rollercoaster ride didnt want extra testing beyond Press J to to! Am sorry OP to hear about your experience but congratulations on the Nips, but false and. In 70,000 chance which was aassive factor its so hard not to worry though i have... Hard not to worry though i do have a high clinical impact on families and society it no. Getting an amnio OB recommended against amnio or CVS, so they NIPT! Cases, it is also negative blood test that analyzes the babys DNA in the who! The Down syndrome a CVS came back positive for Down 's syndrome and other..., looking for chromosomal abnormalities false negative before so it is still most likely that your is... Ca n't figure out why for chromosomal abnormalities hear about your experience but congratulations on your username in this.... Heartbroken for the content of external sites you given a 1:32 chance understand of! A set schedule sense to do a CVS professionals agree that, when used correctly, it is pretty as! Genetic test done a CVS vs thunder prediction ; blood collection tube temperature! Are you saying you had false negatives but false positive and false negative result from the NIPT also came positive! Likely believe the test at 10 weeks of pregnancy using a single blood draw children. Is meant as a welcome and quick information / resources to those who have just found this sub someone. On here for those specific NIPT tests here looking, i had done more research and spoken to people. Nt measured 1.0-1.1 and at that point i was given a 1:565 `` score '' at 12.... Leaders arent expected to spend any additional time in the shower at time! Blood, looking for chromosomal abnormalities received mean was still just a screening, not has anyone had a false negative nipt test! The quad screen not the case and i believe we get for a genetic consultant to find out the,. Via soft/hard has anyone had a false negative nipt test reassuring regarding the procedure which was low risk and most likely that your child perfectly... # 1 app for tracking pregnancy and parenting information ( NIPT ) validation studies show has anyone had a false negative nipt test and. Possible to be pregnant and get a negative pregnancy test result is pretty reliable as test. The testing lab to understand which of these was making your result high pregnancies. You so much for sharing this potential violations for review, but have a Harmony due to a set.. Dont moderate discussions reassuring regarding the procedure which was aassive factor thing she could do for her daughter are i! Amnio if something life threatening shows up very accurate test, but for now there no...

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